Sjogren's SyndromePrint this page
Updated Test Information:
The presence of both SS-A/Ro and SS-B/La antibodies are highly specific serological markers for the diagnosis and disease management of patients with Sjögren’s syndrome or lupus patients with Sjögren's overlap syndrome. SS-A/Ro antibodies can be a marker for SLE and Sjögren’s syndrome. SS-B/La antibodies are highly specific clinical markers for Sjögren’s syndrome, but a small proportion of patients can remain SS-B/La negative. Assay results should be used in conjunction with clinical findings and other serological tests.
|Alternate Specimen Type||
Plasma (Li-Heparin, EDTA, or Citrate)
|Additional Processing Details||
Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs
If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C.
|Unacceptable Specimen Conditions||
Lipemic, hemolyzed or microbially contaminated samples.
Fluorescent enzyme immunoassay (FEIA)
Monday-Saturday, alternating days
|Minimum Sample Volume||
|Pediatric Min. Volume (if applicable)||