Laboratory Services
Sjogren's Syndrome
Print this pageUpdated Test Information:
Test Description |
Sjogren's Syndrome
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Synonym(s) |
Anti-SSB/La, Anti-SSA/Ro
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Test ID |
SJO
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General Information |
The presence of both SS-A/Ro and SS-B/La antibodies are highly specific serological markers for the diagnosis and disease management of patients with Sjögren’s syndrome or lupus patients with Sjögren's overlap syndrome. SS-A/Ro antibodies can be a marker for SLE and Sjögren’s syndrome. SS-B/La antibodies are highly specific clinical markers for Sjögren’s syndrome, but a small proportion of patients can remain SS-B/La negative. Assay results should be used in conjunction with clinical findings and other serological tests.
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Specimen Type |
Serum
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Alternate Specimen Type |
Plasma (Li-Heparin, EDTA, or Citrate)
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Specimen Requirements |
Tiger
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Minimum Sample Volume |
1.5 mL
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Pediatric Min. Volume (if applicable) |
750 uL
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Additional Processing Details |
Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
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Stability |
Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C. |
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Unacceptable Specimen Conditions |
Lipemic, hemolyzed or microbially contaminated samples.
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Methodology |
Fluorescent enzyme immunoassay (FEIA)
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Estimated TAT |
2-5 days
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Testing Schedule |
Monday-Saturday, alternating days
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Test Includes |
SS-A/Ro
SS-B/La |
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CPT Code(s) |
86235x2
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Reference Range |
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Performing Lab |
Incyte Diagnostics
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LOINC Code(s) |
33610-7, 33613-1
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