Laboratory Services

Inhibin A and B, Tumor Marker, Serum

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Updated Test Information:

Test Description
Inhibin A and B, Tumor Marker, Serum
Test ID
INHAB
General Information

Useful for:



  • Aiding in the diagnosis of granulosa cell tumors and mucinous epithelial ovarian tumors

  • Monitoring of patients with granulosa cell tumors and epithelial mucinous-type tumors of the ovary known to secrete inhibin A or overexpress inhibin B

Specimen Type

Serum

Specimen Requirements

  • Preferred: Red Top

  • Acceptable: Serum Gel (SST)

Additional Processing Details

0.6 mL

Stability

  • Refrigerated (preferred): 7 days

  • Frozen: 90 days

Unacceptable Specimen Conditions

Gross hemolysis

Limitations

  • Inhibin values fluctuate during the menstrual cycle. Inhibin levels in premenopausal women should be interpreted with caution

  • Do not interpret serum inhibin levels as absolute evidence of the presence or the absence of malignant disease. Use results in conjunction with information from the clinical evaluation of the patient and other diagnostic procedures

  • Tumor markers are not specific for malignancy and values may vary by testing methodology. The same method should be used to serially monitor patients

  • Some patients who have been exposed to animal antigens, either in the environment or as part of treatment or imaging procedures, may have circulating antianimal antibodies present. These antibodies may interfere with the assay reagents to produce unreliable results

Methodology

  • INHA: Sequential 2-Step Immunoenzymatic Assay

  • INHB: Enzyme-Linked Immunosorbent Assay (ELISA)

Estimated TAT

1 day

Testing Schedule

Monday-Saturday

Test Includes

  • INHA Inhibin A, Tumor Marker

  • INHB Inhibin B

Retention

3 months

CPT Code(s)

83520; 86336

Additional Information
Reference Range

 

Gender Classification Age (years) Inhibin A (pg/mL) Inhibin B (pg/mL)
Male Not Applicable < 2 < 2.0 < 430
2 - 4 < 269
5 - 7 < 184
8 - 10 < 214
11 - 13 < 276
14 - 17 < 273
> 17 < 399
Female < 2 < 4.7 < 111
2 - 4 < 44
5 - 7 < 27
8 - 10 < 67
11 - 13 < 97.5 < 120
14 - 17 < 136
Follicular > 17 < 139
Luteal < 92
Postmenopausal < 2.1 < 10

 

Performing Lab

Mayo

LOINC Code(s)

23883-2, 56940-0