Test Directory

Fetal Fibronectin

Print this page

Updated Test Information:

Test Description
Fetal Fibronectin
Synonym(s)

Rapid fFN, fFN

Test ID
FFN
General Information

Detection of Fetal Fibronectin in cervicovaginal secretions is associated with preterm delivery in symptomatic pregnant women between 24 weeks and 34 weeks, 6 days gestation, and in asymptomatic pregnant women between 22 weeks and 30 weeks, 6 days gestation.

Specimen Type

Cervicovaginal Swab

Specimen Requirements

Collect cervicovaginal secretions using the Hologic Rapid fFN® Test Specimen Collection Kit.

Specimen Collection / Processing Instructions

1.) During a speculum examination, prior to any examination or manipulation of the cervix or the vaginal tract, lightly rotate the sterile swab across the posterior fornix of the vagina for approximately 10 seconds to absorb cervicovaginal secretions. Subsequent attempts to saturate the swab may invalidate the test.
2.) Remove the Hologic Perinatal Swab (sterile, polyester-tipped swab) and immerse tip in buffer. Break the shaft (at the score) even with the top of the tube.
3.) Align the shaft with the hole inside the tube cap and push down tightly over the shaft, sealing the tube. Warning: The shaft must be aligned to avoid leakage.
4.) Write the patient’s name and other identifying information required on the specimen transport tube label.
5.) Send the tube to the laboratory for testing. Transport specimens at 2° to 25°C, or frozen.

Stability

8 hours at 20-25 °C 
3 days at 2-8 °C 
3 months at -20 °C (± 5 °C)

Unacceptable Specimen Conditions

Specimens received at temperatures >25 °C, subjected to more than one freeze-thaw cycle or use of a non-Hologic Rapid fFN® Test Specimen Collection Kit.

Limitations

Patients with suspected or known placental abruption, placenta previa or moderate to gross vaginal bleeding. Specimens contaminated with lubricants, soaps, disinfectants or creams.

Department (code)

Chemistry

Methodology

Semi-Quantitative Immunoassay/Immunosorbent

Estimated TAT

0-1 Days

Testing Schedule

Monday-Saturday

CPT Code(s)

82731

Performing Lab

Incyte Diagnostics

LOINC Code(s)

57069-7, 49051-6, 48039-2