Laboratory Services

Cytomegalovirus (CMV) Antibodies, IgG, Serum

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Updated Test Information:

Test Description
Cytomegalovirus (CMV) Antibodies, IgG, Serum
Synonym(s)

CMV (Cytomegalovirus) Antibody; Torch IgG

Test ID
CMVG
General Information

Useful for determining whether a patient (especially transplant recipients, organ and blood donors) has had a recent infection or previous exposure to cytomegalovirus

Specimen Type

Serum

Specimen Requirements

  • Preferred: Serum Gel

  • Acceptable: Red Top

Stability

  • Refrigerated (preferred): 14 days

  • Frozen: 14 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

  • Heat-inactivated specimen

Limitations

  • Sera drawn very early during the acute stage of infection may have undetectable levels of cytomegalovirus (CMV) IgG. The CMV IgG assay should not be used alone to diagnose CMV infection. Results should be considered in conjunction with clinical presentation, patient history, and other laboratory findings. In cases of suspected disease, submit a second specimen for testing in 10 to 14 days

  • The performance characteristics of this assay have not been evaluated in immunosuppressed or organ transplant recipients and have not been established for cord blood or for testing of neonates

  • Immune complexes or other immunoglobulin aggregates present in patient samples may cause increased nonspecific binding and produce false-positive results

  • Potential cross-reactivity for CMV with human chorionic gonadotropin, HIV IgG, multiple myeloma IgG, rheumatoid factor IgM, and Toxoplasma gondii IgG have not be ruled out

Methodology

Multiplex Flow Immunoassay (MFI)

Estimated TAT

1-3 days

Testing Schedule

Monday-Saturday

Retention

14 days

CPT Code(s)

86644

Additional Information
Minimum Sample Volume

0.4 mL

Reference Range

Negative

Performing Lab

Mayo

LOINC Code(s)

13949-3