Laboratory Services

Cortisol, Random

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Updated Test Information:

Test Description
Cortisol, Random
Test ID
COR
General Information
Establish the diagnosis of adrenocortical insufficiency, Addison's disease, adrenocortical hypersecretion, Cushing's syndrome. Malfunction of the organs in the hypothalamic-pituitary-adrenal cortex axis will result in alteration of the cortisol levels.
Specimen Type
Serum
Alternate Specimen Type
Red, Li-heparin plasma
Specimen Requirements
SST
Specimen Collection / Processing Instructions
SST - Due to the circadian rhythm of cortisol levels in serum and plasma, the sample collection time must be noted.
Minimum Sample Volume
1 mL
Pediatric Min. Volume (if applicable)
500 uL
Additional Processing Details
Due to the circadian rhythm of cortisol levels in serum and plasma, the sample collection time must be noted.
Stability
24 hours at 20-25˚C
4 days at 2-8˚C
12 months at -20˚C. Freeze only once.
Unacceptable Specimen Conditions
Citrate plasma samples
Limitations
This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.
Methodology
Electrochemiluminescence immunoassay ECLIA
Estimated TAT
0-2 days
Testing Schedule
Monday-Saturday
CPT Code(s)
82533
Reference Range
6-10 am: 4.82-19.5 ug/dL
4-8 pm: 2.47-11.9 ug/dL
Performing Lab
Incyte Diagnostics
LOINC Code(s)
2143-6