Laboratory Services

CLL (Chronic Lymphocytic Leukemia) FISH Panel, SLL (Small Lymphocytic lymphoma)

Name: Incyte Diagnostics
Address: 13103 E Mansfield Ave, Spokane Valley, Washington, 99216, USA
Telephone: +1-If-you-have-questions-regarding-your-bill-or-would-like-to-make-a-payment,-please-visit-our-Billing-page-by-clicking-"Pay-Online"-at-the-top-of-the-page-For-other-inquiries,-please-call-us-at-509-892-2700

Updated Test Information:

Test Description	CLL (Chronic Lymphocytic Leukemia) FISH Panel, SLL (Small Lymphocytic lymphoma)
Synonym(s)	CLL, SLL
General Information	Probes: 13q14/13q34/CEP 12, TP53/ATM (17p13/11q22.3), CCND1/IGH t(11;14), SEC63.MYB (6q21/6q23), (probe sets may be ordered separately) Disease(s): Chronic Lymphocytic Leukemia/small lymphocytic lymphoma (CLL/SLL)
Specimen Requirements	Bone Marrow Aspirate and Peripheral Blood 2-5 mL Sodium Heparin tube (preferred) EDTA tube (acceptable) Fixed-cell pellet from cytogenetic analysis slides with metaphase and/or interphase nuclei. (If sending slides please send at least 6 slides for testing)
Additional Processing Details	Transport to the testing lab at room temp is acceptable. Do not allow sample to overheat or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
Required Information	Complete the Incyte Diagnostics hematology requisition with the patient's demographics and relevant clinical history. Label the specimen containers with patient's full name, second unique identifier, and specimen site/source. Please provide a copy of the patient's complete blood count (CBC) report.
Unacceptable Specimen Conditions	Specimen containers without two (2) patient identifiers, specimens submitted in inappropriate collection media, frozen specimens.
Department (code)	FISH
Methodology	Fluorescence In Situ Hybridization (FISH)
Estimated TAT	3–5 working days from receipt
Testing Schedule	Monday–Friday
Retention	7 days after release of final report
CPT Code(s)	88377x4 manual
Additional Information	Clinical Significance: The CLL/SLL FISH panel is used for the detection of chromosome aberrations observed in chronic lymphocytic leukemia/small lymphocytic lymphoma, which are useful prognosis and prediction of time to treatment in CLL patients when used in combination with other clinical and diagnostic findings. IGH/CCND1 is used to rule out mantle cell leukemia/lymphoma. If Flow Cytometry studies are also being ordered, it is preferable to submit an EDTA (purple top) tube specifically for Flow Cytometry. If only one tube can be submitted, please submit one sodium heparin (green top) tube for both FISH and Flow Cytometry studies.