Test Directory

Beta Catenin

Clone:

14 (Bellevue)

Synonym(s):

ß-Catenin

Application:

Nuclear staining is seen in fibroblasts and utilized to distinguish between fibromatosis, low grade fibromyxoid sarcoma, and other myofibroblastic and fibroblastic processes. It can also be useful for classifying subtypes of hepatocellular adenoma and focal nodular hyperplasia.

Specimen Type:

Formalin-fixed, paraffin-embedded tissue blocks (FFPE). If tissue blocks are not available, unstained slides are acceptable (please submit 1–2 slides per antibody to be tested, cuts must be 4 microns thick).

Collection Procedure:

Tissue removed during a surgical procedure and placed in 10% NBF soon after removal from the patient. Appropriate tissue for requested staining.

Required Information:

Complete the Incyte Diagnostics requisition with the patient's demographics and relevant clinical history.

Specimen Stability:

Ambient: Indefinite

Unacceptable Specimen:

Slides or paraffin blocks with no tissue remaining. Samples fixed in fixatives other than 10% neutral buffered formalin. Paraffin blocks that have been overheated or frozen.

Department:

Histology

Method:

IHC, Ventana Ultra Stainer

Turnaround:

12 business days from receipt

Performed:

Monday–Saturday

Retention:

Blocks: 10 years
Slides: 10 years

CPT Code:*

88342
88341

Test Code(s):

BETACAT

*The listed CPT codes are for reference use only. Final coding is based on CPT guidelines and individual circumstances.

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