Herpes Simplex Virus 1 and 2, Qualitative PCR, Blood
Herpes Simplex Virus Detection by Real-Time PCR; HSV (Herpes Simplex Virus) by PCR (Polymerase Chain Reaction); HSV Detection by Real-Time PCR; HSV PCR
Direct detection and differentiation of HSV-1 and HSV-2 DNA in whole blood specimens from symptomatic patients who are suspected to have disseminated disease
Diagnosis of HSV infection in symptomatic patients
This test is not intended to be used for prenatal screenings
This test is intended for symptomatic patients with evidence of disseminated herpes simplex virus (HSV) infection. It should not be used to determine if a patient has been exposed to HSV at some point in the past; rather, it should be ordered when there is a suspicion for active infection.
If herpes simplex virus (HSV) is suspected in sources other than blood, order HERPV / Herpes Simplex Virus 1 and 2, Qualitative PCR, Varies
If HSV is suspected in cerebrospinal fluid (CSF), order HSVC / Herpes Simplex Virus (HSV), Molecular Detection, PCR, Spinal Fluid
EDTA Whole Blood
Refrigerated: 7 days
Unacceptable Specimen Conditions
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
A negative result does not eliminate the possibility of herpes simplex virus (HSV) infection. There is a risk of a falsenegative result due to improperly collected or transported blood specimens
There is a risk of a false-positive result due to contamination by target organisms or their nucleic acids, which may be introduced at the point of sample collection or testing. Every effort to minimize the risk of contamination should be taken
The ARIES HSV 1 and 2 assay may not detect a coinfection of HSV-1 and -2 in specimens where the 2 virus types are not equally represented in clinical specimens. The ARIES HSV-1 and -2 assay detects and differentiates between HSV-1 and HSV-2 only. It does not detect or differentiate any other herpes viruses (eg, cytomegalovirus [CMV], Epstein-Barr virus [EBV]). This assay does not distinguish between infectious HSV-1or -2, and the presence of nucleic acid (ie, noninfectious viral particles)
Results should be interpreted in conjunction with other clinical and laboratory findings.