Laboratory Services

Glomerular Basement Membrane Antibody

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Updated Test Information:

Test Description
Glomerular Basement Membrane Antibody

GBM, ANCA, Antineutrophil cytoplasmic autoantibodies, Goodpasture Syndrome

Test ID
General Information

Glomerular Basement Membrane (GBM) antibodies are useful in the diagnosis and disease management of patients with primary systemic small vessel vasculitides. The presence of GBM is required for the diagnosis of Goodpasture syndrome and anti-GBM-disease. Assay results should be used in conjunction with clinical findings and other serological tests.

Specimen Type


Alternate Specimen Type

Plasma (Li-Heparin, EDTA, or Citrate)

Specimen Requirements


Minimum Sample Volume

1 mL

Pediatric Min. Volume (if applicable)

500 uL

Additional Processing Details

Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.


Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs
If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C.

Unacceptable Specimen Conditions

Lipemic, hemolyzed or microbially contaminated samples.


Fluorescent enzyme immunoassay (FEIA)

Estimated TAT

2-5 days

Testing Schedule

Monday-Saturday, alternating days

CPT Code(s)


Reference Range

Negative < 7 U/mL
Equivocal 7-10 U/mL
Positive > 10 U/mL

Performing Lab

Incyte Diagnostics

LOINC Code(s)